Gehry, now 75, comes from a working-class Jewish background in Canada. Keswick Jencks was a member of an upper-class Scottish family, linked by marriage to the Jardine Matheson company, which virtually ran Hong Kong when it was a British colony.The architect said he agonised over designs for the building but recalls that the eventual shape came after Keswick Jencks appeared to him in a dream and told him to "calm it down". But its wavy stainless-steel roof and central lighthouse-like tower suggest that it is something very different. Tucked away in the grounds of a hospital in Dundee, Maggie's Cancer Care Centre ought to be just another ordinary and anonymous NHS building. And yesterday its bravura style was recognised when it was awarded the nation's top accolade for building design.Naming the centre as its Building of the Year, the Royal Fine Art Commission Trust, which chose from buildings built last year, said it possessed "outstanding architectural features" but was also a building of the "highest social significance" in its role providing care for cancer sufferers.The building has a poignant story: it is named after the late Maggie Keswick Jencks, the Scottish artist, designer and landscape gardener, who died from breast cancer in 1995. The current owner, who is anonymous, bought the bulk of the group from Serge Sabarsky, but, without the space to hang them together, has decided to sell.

It will be the first opportunity for buyers to buy any of them individually.Two works by his fellow Austrian, Gustav Klimt, which were both seized by the Nazis during the war, are being sold by families to whom they have been returned only recently.The large painting by Claude Monet is a beautiful late waterlilies scene from this Nymph? series. Painted between 1914 and 1917 at his home in Giverny where he transformed the gardens into a horticultural paradise, it is estimated at up to £6m.Other works of note include a scene of horses and riders by Edgar Degas, a painting of crabs by Vincent van Gogh painted just after he fell out with Gauguin and cut off part of his ear, and the Modigliani, a typically elongated portrait of a boy.. She said: "What matters is not to lose the joy of living in the fear of dying."Gehry met the Jencks in the late 1970s when they were living in California, where he is still based. In a recent interview, he described his first impression of Keswick Jencks as "this fancy lady from Britain, with family titles and all that stuff, to which I was susceptible to because of my upbringing".

Lord Fawsley said: "People suffering major threats to health do not wish to be written off but rather they need constructive and loving care Above all, they need a place of beauty in which to rest. We all owe a great aesthetic and social debt to Maggie, Frank and Charles for this magnificent contribution to the relief of human suffering."Keswick Jencks had wanted to provide a supplementary service to orthodox NHS treatment, where patients could get support and complementary treatment. "Although small, it has an astonishing variety of outstanding architectural features, including its undulating roof, its space, its landmark tower and its command of one of the most beautiful views in Britain seen through a specially constructed and shaped picture window," he said.The design takes its themes from the view of the Tay estuary; the central tower resembles a lighthouse while the steel roof appears to change colour according to the light and is said to appear like waves breaking on rocks.The building, at Ninewells Hospital in Dundee, is the third in a series of 10 being established around the country by the organisation set up in memory of Keswick Jencks, Maggie's Centres. Encouraged by the success of the Gehry project and at the invitation of her husband, the American architectural critic and historian, Charles Jencks, each building is being designed by the world's leading architects.They include Lord Rogers, working on the London centre at Charing Cross Hospital; Zaha Hadid, who is creating a centre in Kirkcaldy, Fife; Piers Gough, working in Nottingham and Daniel Libeskind, the architect of the World Trade Centre site, working at Addenbroke's Hospital in Cambridge.The centres are staffed by unpaid volunteers and they help recently diagnosed people as well as those in the later stages of the disease, offering sympathy and advice. The building, designed by the cutting-edge London practice Future Systems, who were responsible for the space-age media centre at Lords cricket ground, as a monument to consumer culture and urban buzz, did take the commission's specialist award for retail innovation.Lord St John of Fawsley, the chairman of the trust, said Maggie's Cancer Care Centre was "just as great" as the other building for which Gehry is renowned, the Guggenheim Museum in Bilbao. The building was designed free by her great friend, Gehry, and it is his first work in the United Kingdom.Significantly, the judges chose Maggie's Cancer Care Centre ahead of the building which many might have tipped for the award but which represents a different kind of architectural enterprise, the shining, "bubble-wrapped" Selfridges building in Birmingham.

"It is probably the most important Schiele on paper ever to come on the market," Miss Clore said It is expected to make up to £1.8m. It is similar to a work which made $6m (£3.3m, three times its estimate, a few months ago.The 15 works on paper by Schiele, an Austrian artist who died at the age of 28 in 1918 but whose stock has risen considerably in recent years, are regarded as important as they cover all the main themes in his work.There is a self-portrait, a portrait of the composer Schoenberg and several erotic works including the most significant gouache in the sale, Liebespaar , depicting lovers in an embrace. A second Picasso, Plante de Tomate , is being sold from the collection of Ray Stark, the Hollywood producer of films including Funny Girl and Steel Magnolias, who died this year. It was painted the year before the great Impressionist show of 1874, making it "a significant milestone in the early development of the Impressionist", and is estimated to fetch between £6m and £8m.A second work by Renoir, a female nude, Jeune Femme se baignant , is expected to make up to £5m.A rare large canvas from the 1930s by Picasso depicts his lover, Marie-Th?se and is expected to make up to £3m. There's Art Fortnight and Grosvenor House [art fair] as well as Ascot and Wimbledon," Miss Clore said.The most valuable painting on offer is a luminous portrait by Pierre-Auguste Renoir, which belongs to an important group of commissioned portraits that established him at the forefront of the Parisian avant-garde. For American sellers, the strong pound made it more sensible to sell in the UK.In addition, the sale is the first big event of Art Fortnight, a programme of exhibitions and auctions involving around 80 galleries and designed to celebrate London's role in the international art market."London in June is a very compelling venue.